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EBP Antibody(C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15125
Clone Names 100318237
Peptide ID 100318237
Additional Information
Gene ID 10682
Other Names 3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase, Cholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, D8-D7 sterol isomerase, Emopamil-binding protein, EBP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EBP
Function Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is an integral membraneprotein of the endoplasmic reticulum. It is a high affinity bindingprotein for the antiischemic phenylalkylamine Ca2+ antagonist[3H]emopamil and the photoaffinity label [3H]azidopamil. It issimilar to sigma receptors and may be a member of a superfamily ofhigh affinity drug-binding proteins in the endoplasmic reticulum ofdifferent tissues. This protein shares structural features withbacterial and eukaryontic drug transporting proteins. It has fourputative transmembrane segments and contains two conservedglutamate residues which may be involved in the transport ofcationic amphiphilics. Another prominent feature of this protein isits high content of aromatic amino acid residues (>23%) in itstransmembrane segments. These aromatic amino acid residues havebeen suggested to be involved in the drug transport by theP-glycoprotein. Mutations in this gene cause Chondrodysplasiapunctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).


Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Ausavarat, S., et al. Eur J Dermatol 18(4):391-393(2008)Steijlen, P.M., et al. Br. J. Dermatol. 157(6):1225-1229(2007)Guggenberger, C., et al. J. Steroid Biochem. Mol. Biol. 104 (3-5), 105-109 (2007) :Rakheja, D., et al. Pediatr. Dev. Pathol. 10(2):142-148(2007)

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$ 80.00
Cat# BP19661b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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