|Other Names||Zinc finger protein 185, LIM domain protein ZNF185, P1-A, ZNF185|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the regulation of cellular proliferation and/or differentiation.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, focal adhesion|
|Tissue Location||Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood|
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Zinc-finger proteins bind nucleic acids and play importantroles in various cellular functions, including cell proliferation,differentiation, and apoptosis. This gene encodes a LIM-domain zincfinger protein. The LIM domain is composed of two contiguous zincfinger domains, separated by a two-amino acid residue hydrophobiclinker. The LIM domain mediates protein:protein interactions.Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Zhang, J.S., et al. Oncogene 26(1):111-122(2007)Medina, P.P., et al. Hum. Mol. Genet. 14(7):973-982(2005)Vanaja, D.K., et al. Cancer Res. 63(14):3877-3882(2003)Mallon, A.M., et al. Genome Res. 10(6):758-775(2000)Heiss, N.S., et al. Genomics 43(3):329-338(1997)
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