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STARD13 Blocking Peptide(Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y3M8 |
|---|---|
| Other Accession | NP_443083.1, NP_821074.1, NP_821075.1 |
| Gene ID | 90627 |
|---|---|
| Other Names | StAR-related lipid transfer protein 13, 46H232, Deleted in liver cancer 2 protein, DLC-2, Rho GTPase-activating protein, START domain-containing protein 13, StARD13, STARD13, DLC2, GT650 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 559-573 of HUMAN STARD13 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | STARD13 |
|---|---|
| Synonyms | DLC2, GT650 |
| Function | GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet |
| Tissue Location | Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that contains a sterile alpha motif domain in the N-terminus, an ATP/GTP-binding motif, a GTPase-activating protein domain, and a STAR-related lipid transfer domain in the C-terminus. The gene is located in a region of chromosome 13 that has loss of heterozygosity in hepatic cancer. At least three alternatively spliced transcript variants have been described for this gene.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Yasuno, K., et al. Nat. Genet. 42(5):420-425(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Xiaorong, L., et al. BMC Cancer 8, 205 (2008) :
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