|Other Accession||Q8VCK3, Q9NRH3, Q32KM1, P23330, P83888, P83887, Q0VCD2, NP_001061.2|
|Other Names||Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1, TUBG1, TUBG|
|Target/Specificity||The synthetic peptide sequence is selected from aa 38-51 of HUMAN TUBG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010)
Alvarado-Kristensson, M., et al. Nat. Cell Biol. 11(9):1081-1092(2009)
Zhang, X., et al. J. Cell. Sci. 122 (PT 13), 2240-2251 (2009) :
Haren, L., et al. PLoS ONE 4 (6), E5976 (2009) :
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