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EOMES Blocking Peptide(N-term)

Synthetic peptide

Product Information
Primary Accession O95936
Other Accession NP_005433.2
Additional Information
Gene ID 8320
Other Names Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2, EOMES, TBR2
Target/Specificity The synthetic peptide sequence is selected from aa 43-57 of HUMAN EOMES
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TBR2
Function Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.
Cellular Location Nucleus.
Tissue Location Expressed in CD8+ T-cells.
Research Areas
Citations (0)

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This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.


Wang, H.T., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26(1):31-34(2010)
Narayanan, S., et al. PLoS ONE 5 (5), E10636 (2010) :
D'Cruz, L.M., et al. Semin. Immunol. 21(2):92-98(2009)
Sessa, A., et al. Neuron 60(1):56-69(2008)
Araki, Y., et al. J. Immunol. 180(12):8102-8108(2008)

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$ 80.00
$ 99.00
Cat# BP19703a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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