PCYT1A Blocking Peptide(C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P49585 |
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Other Accession | P19836, P49586, P49584, NP_005008.2 |
Gene ID | 5130 |
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Other Names | Choline-phosphate cytidylyltransferase A, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A, PCYT1A, CTPCT, PCYT1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 296-309 of HUMAN PCYT1A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PCYT1A |
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Synonyms | CTPCT, PCYT1 |
Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum. Nucleus Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836} |
Tissue Location | Brain, placenta, liver, fetal and adult lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PCYT1A controls phosphatidylcholine synthesis.
References
Mostowska, A., et al. J. Med. Genet. (2010) In press :
Mostowska, A., et al. Eur. J. Oral Sci. 118(4):325-332(2010)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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