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NCAPH2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6IBW4
Other Accession Q9BUT3
Clone Names 6022605
Peptide ID 6022605
Additional Information
Gene ID 29781
Other Names Condensin-2 complex subunit H2, Chromosome-associated protein H2, hCAP-H2, Kleisin-beta, Non-SMC condensin II complex subunit H2, NCAPH2, CAPH2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1973c was selected from the Center region of human NCAPH2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAPH2
Function Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development (By similarity).
Cellular Location Nucleus. Chromosome. Note=Distributed along the arms of chromosomes assembled in vivo and in vitro
Research Areas
Citations (0)

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Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.


Ono,T., et al. Cell 115 (1), 109-121 (2003).Schleiffer,A., et al. Mol. Cell 11 (3), 571-575 (2003).Loftus, B.J., et al., Genomics 60(3):295-308 (1999).

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$ 80.00
Cat# BP1973c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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