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UFC1 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y3C8 |
|---|---|
| Other Accession | Q6BBI8, Q9CR09, Q5E953, NP_057490.2 |
| Gene ID | 51506 |
|---|---|
| Other Names | Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1, UFC1 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 17-31 of HUMAN UFC1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941} |
|---|---|
| Function | E1-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776). Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).
References
Liu, G., et al. J. Struct. Funct. Genomics 10(2):127-136(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Komatsu, M., et al. EMBO J. 23(9):1977-1986(2004)
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