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RPS6 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P62753
Clone Names 61228165
Peptide ID 61228165
Additional Information
Gene ID 6194
Other Names 40S ribosomal protein S6, Phosphoprotein NP33, RPS6
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1977b was selected from the C-term region of human RPS6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS6
Function May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Research Areas
Citations (0)

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Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 is a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. This protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA.

References

Lott J.B., Gene 65:31-39(1988).Heinze H., J. Biol. Chem. 263:4139-4144(1988).Antoine M., Hum. Mol. Genet. 1:565-570(1992).Pata I., Gene 121:387-392(1992).

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$ 80.00
Cat# BP1977b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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