|Other Names||Rho guanine nucleotide exchange factor 16, Ephexin-4, ARHGEF16, EPHEXIN4, NBR|
|Target/Specificity||The synthetic peptide sequence is selected from aa 202-214 of HUMAN ARHGEF16|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.|
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Provided below are standard protocols that you may find useful for product applications.
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.
Hiramoto-Yamaki, N., et al. J. Cell Biol. 190(3):461-477(2010)
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002)
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