|Other Names||Zinc finger protein 395, HD-regulating factor 2, HDRF-2, Huntington disease gene regulatory region-binding protein 2, HD gene regulatory region-binding protein 2, HDBP-2, Papillomavirus regulatory factor 1, PRF-1, Papillomavirus-binding factor, ZNF395, HDBP2, PBF|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1979b was selected from the HDRF-2 region of human HDBP2(HDRF-2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in papillomavirus genes transcription.|
|Cellular Location||Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Papillomavirus Regulatory Factor 1/HDBP2 is a novel transcription factor shuttling between nucleus and cytoplasm and binds to the specific GCCGGCG, which is an essential cis-element for Huntington's disease gene expression.
Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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