GAPT Blocking Peptide(Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N292 |
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Other Accession | NP_689900.1 |
Gene ID | 202309 |
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Other Names | Protein GAPT, Growth factor receptor-bound protein 2-binding adapter protein, transmembrane, GAPT, C5orf29 |
Target/Specificity | The synthetic peptide sequence is selected from aa 99-112 of HUMAN GAPT |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GAPT |
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Synonyms | C5orf29 |
Function | Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). |
Cellular Location | Cell membrane; Single-pass membrane protein |
Tissue Location | Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity).
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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