|Other Accession||Q9WU20, Q60HE5, Q5I598, NP_005948.3|
|Other Names||Methylenetetrahydrofolate reductase, MTHFR|
|Target/Specificity||The synthetic peptide sequence is selected from aa 281-292 of HUMAN MTHFR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Singh, K., et al. J Postgrad Med 56(4):267-269(2010)
Harisha, P.N., et al. J Neurosurg Pediatr 6(4):364-367(2010)
Wu, H.C., et al. Anticancer Res. 30(9):3573-3577(2010)
Magnowski, P., et al. Ginekol. Pol. 81(7):506-510(2010)
Kristensen, M.H., et al. J. Int. Med. Res. 38(3):870-883(2010)
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