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NFE2L3 Blocking Peptide(C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q9Y4A8
Other Accession NP_004280.5
Additional Information
Gene ID 9603
Other Names Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3, NFE2L3, NRF3
Target/Specificity The synthetic peptide sequence is selected from aa 681-694 of HUMAN NFE2L3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFE2L3
Synonyms NRF3
Function Activates erythroid-specific, globin gene expression.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}
Tissue Location Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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Background

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Zhang, Y., et al. J. Biol. Chem. 284(5):3195-3210(2009)

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$ 80.00
$ 99.00
Cat# BP19864B
Size:
Quantity:
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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