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LRRC19 Blocking Peptide(C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H756 |
|---|---|
| Other Accession | NP_075052.1 |
| Gene ID | 64922 |
|---|---|
| Other Names | Leucine-rich repeat-containing protein 19, LRRC19 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 304-318 of HUMAN LRRC19 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LRRC19 (HGNC:23379) |
|---|---|
| Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines (PubMed:19679103, PubMed:25026888). In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in renal collecting duct epithelial cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Chai, L., et al. Biochem. Biophys. Res. Commun. 388(3):543-548(2009)
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