TMEM59L Blocking Peptide(C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UK28 |
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Other Accession | NP_036241.1 |
Gene ID | 25789 |
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Other Names | Transmembrane protein 59-like, Brain-specific membrane-anchored protein, TMEM59L, BSMAP, C19orf4 |
Target/Specificity | The synthetic peptide sequence is selected from aa 241-254 of HUMAN TMEM59L |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TMEM59L |
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Synonyms | BSMAP, C19orf4 |
Function | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. |
Cellular Location | Golgi apparatus membrane; Single-pass type I membrane protein |
Tissue Location | Expressed preferentially at high level in the brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system.
References
Elson, G.C., et al. Biochem. Biophys. Res. Commun. 264(1):55-62(1999)
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