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BCL9L Blocking Peptide(N-term)

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession Q86UU0
Other Accession NP_872363.1
Additional Information
Gene ID 283149
Other Names B-cell CLL/lymphoma 9-like protein, B-cell lymphoma 9-like protein, BCL9-like protein, Protein BCL9-2, BCL9L, DLNB11
Target/Specificity The synthetic peptide sequence is selected from aa 162-176 of HUMAN BCL9L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL9L
Synonyms DLNB11
Function Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).
Cellular Location Nucleus
Tissue Location Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor
Research Areas
Citations (0)

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Background

Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).

References

Miller, T.C., et al. J. Mol. Biol. 401(5):969-984(2010)
Fritzmann, J., et al. Gastroenterology 137(1):165-175(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sampietro, J., et al. Mol. Cell 24(2):293-300(2006)
Brembeck, F.H., et al. Genes Dev. 18(18):2225-2230(2004)

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$ 80.00
Cat# BP19875a
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