C17orf60 Blocking Peptide(C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q7Z6M3 |
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Other Accession | NP_001078892.1 |
Gene ID | 284021 |
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Other Names | Allergin-1, Allergy inhibitory receptor 1, Mast cell antigen 32, MCA-32, Mast cell immunoglobulin-like receptor 1, MILR1, C17orf60, MCA32 |
Target/Specificity | The synthetic peptide sequence is selected from aa 282-295 of HUMAN MILR1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MILR1 |
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Synonyms | C17orf60, MCA32 |
Function | Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T- cells or natural killer cells), peripheral blood basophils and mast cells (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Hitomi, K., et al. Nat. Immunol. 11(7):601-607(2010)
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