|Other Names||Allergin-1, Allergy inhibitory receptor 1, Mast cell antigen 32, MCA-32, Mast cell immunoglobulin-like receptor 1, MILR1, C17orf60, MCA32|
|Target/Specificity||The synthetic peptide sequence is selected from aa 282-295 of HUMAN MILR1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein is unknown.
Hitomi, K., et al. Nat. Immunol. 11(7):601-607(2010)
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