|Other Names||Cadherin-like protein 26, Cadherin-like protein VR20, CDH26|
|Target/Specificity||The synthetic peptide sequence is selected from aa 833-846 of HUMAN CDH26|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ferreira, M.A., et al. Allergy 64(11):1623-1628(2009)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
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