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AMPH Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession P49418
Other Accession O08838, Q7TQF7, NP_647477.1
Additional Information
Gene ID 273
Other Names Amphiphysin, AMPH, AMPH1
Target/Specificity The synthetic peptide sequence is selected from aa 155-168 of HUMAN AMPH
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AMPH
Synonyms AMPH1
Function May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton
Tissue Location Neurons, certain endocrine cell types and spermatocytes
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

References

He, P., et al. Amino Acids 38(4):1209-1218(2010)
Liu, L., et al. Protein Pept. Lett. 17(2):246-253(2010)
Hou, T., et al. J. Mol. Biol. 376(4):1201-1214(2008)
Zhou, P., et al. Biopolymers 90(6):792-802(2008)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)

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$ 277.78
Cat# BP19926C
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