SERPINB9 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P50453 |
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Other Accession | NP_004146.1 |
Gene ID | 5272 |
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Other Names | Serpin B9, Cytoplasmic antiproteinase 3, CAP-3, CAP3, Peptidase inhibitor 9, PI-9, SERPINB9, PI9 |
Target/Specificity | The synthetic peptide sequence is selected from aa 137-150 of HUMAN SERPINB9 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SERPINB9 |
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Synonyms | PI9 |
Function | Granzyme B inhibitor. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995 [PubMed 8530382]).
References
Rousalova, I., et al. Int. J. Oncol. 36(1):275-283(2010)
Jiang, X., et al. Endocrinology 149(11):5366-5373(2008)
Bots, M., et al. Hum. Immunol. 68(12):959-964(2007)
Kummer, J.A., et al. Cell Death Differ. 14(8):1486-1496(2007)
Jiang, X., et al. Oncogene 26(28):4106-4114(2007)
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