|Other Accession||Q2QLE3, Q90YH9, Q2YDE9, NP_690042.1, Q2QLB2, Q09YJ2|
|Other Names||Testin, TESS, TES|
|Target/Specificity||The synthetic peptide sequence is selected from aa 56-70 of HUMAN TES|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.|
|Cellular Location||Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene.
Qiu, H., et al. Cancer Sci. 101(5):1255-1260(2010)
Gunduz, E., et al. Arch. Otolaryngol. Head Neck Surg. 135(3):254-260(2009)
Zhong, Y., et al. Mol. Cell. Biochem. 320 (1-2), 85-92 (2009) :
Huang, W., et al. Ai Zheng 27(9):984-988(2008)
Boeda, B., et al. Mol. Cell 28(6):1071-1082(2007)
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