|Other Names||Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, GP110|
|Target/Specificity||The synthetic peptide sequence is selected from aa 383-397 of HUMAN ADRM1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.|
|Cellular Location||Cytoplasm. Nucleus.|
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The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.
Mazumdar, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13854-13859(2010)
Elangovan, M., et al. Biochem. Biophys. Res. Commun. 396(2):425-428(2010)
Chen, X., et al. Mol. Cell 38(3):404-415(2010)
Kim, T., et al. Biochem. Biophys. Res. Commun. 390(3):585-590(2009)
Chen, W., et al. Zhonghua Zhong Liu Za Zhi 31(11):815-819(2009)
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