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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SLC5A11 Blocking Peptide (N-term)   

SLC5A11 Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession Q8WWX8
Other Accession NP_443176.2
Additional Information
Gene ID 115584
Other Names Sodium/myo-inositol cotransporter 2, Na(+)/myo-inositol cotransporter 2, Sodium-dependent glucose cotransporter, Sodium/glucose cotransporter KST1, Sodium/myo-inositol transporter 2, SMIT2, Solute carrier family 5 member 11, SLC5A11 {ECO:0000312|EMBL:EAW557811}
Target/Specificity The synthetic peptide sequence is selected from aa 14-25 of HUMAN SLC5A11
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC5A11 {ECO:0000312|EMBL:EAW55781.1}
Function Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
Cellular Location Membrane {ECO:0000250|UniProtKB:Q28728}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q28728}
Tissue Location Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes
Research Areas
Citations (0)

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Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Tsai, L.J., et al. Tissue Antigens 71(2):114-126(2008)
Coady, M.J., et al. J. Biol. Chem. 277(38):35219-35224(2002)
Roll, P., et al. Gene 285 (1-2), 141-148 (2002) :

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$ 80.00
$ 99.00
Cat# BP19993a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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