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ATP1A3 Blocking Peptide (Center)

Synthetic peptide

Product Information
Primary Accession P13637
Other Accession P06687, Q6PIC6, P24797, NP_689509.1
Additional Information
Gene ID 478
Other Names Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3, ATP1A3
Target/Specificity The synthetic peptide sequence is selected from aa 820-833 of HUMAN ATP1A3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP1A3
Function This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit.


Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010)
Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010)
Hauck, C., et al. Eur. J. Pharmacol. 622 (1-3), 7-14 (2009) :
Blanco-Arias, P., et al. Hum. Mol. Genet. 18(13):2370-2377(2009)
Goldstein, I., et al. Biol. Psychiatry 65(11):985-991(2009)

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$ 80.00
$ 99.00
Cat# BP20032c
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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