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SDCBP Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession O00560
Other Accession Q9JI92, O08992, NP_005616.2
Additional Information
Gene ID 6386
Other Names Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1, SDCBP, MDA9, SYCL
Target/Specificity The synthetic peptide sequence is selected from aa 7-20 of HUMAN SDCBP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MDA9, SYCL
Function Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
Cellular Location Cell junction, focal adhesion. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Melanosome. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum Colocalized with actin stress fibers. Also found in the nucleus Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta
Research Areas
Citations (0)

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The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].


Boukerche, H., et al. Oncogene 29(21):3054-3066(2010)
Qian, X.L., et al. Yi Chuan 32(3):235-241(2010)
Hwangbo, C., et al. Cancer Res. 70(4):1645-1655(2010)
Beekman, J.M., et al. Blood 114(18):3917-3927(2009)
Sira, M.M., et al. Int. Immunol. 21(9):1013-1023(2009)

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$ 80.00
$ 99.00
Cat# BP20056a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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