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GDI1 Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession P31150
Other Accession P50398, P50396, Q8HXX7, P21856, NP_001484.1
Additional Information
Gene ID 2664
Other Names Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDI1, GDIL, OPHN2, RABGDIA, XAP4
Target/Specificity The synthetic peptide sequence is selected from aa 430-443 of HUMAN GDI1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDI1
Function Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Cellular Location Cytoplasm. Golgi apparatus, trans-Golgi network
Tissue Location Brain; predominant in neural and sensory tissues.
Research Areas
Citations (0)

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GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.


Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)
Massignan, T., et al. Mol. Cell Proteomics 9(4):611-622(2010)
Chen, Y., et al. Biochem. J. 422(2):229-235(2009)
Zhang, K.J., et al. Yi Chuan 30(5):590-594(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 80.00
$ 99.00
Cat# BP20083b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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