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TFIP11 Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession Q9UBB9
Other Accession A1XD95, NP_036275.1
Additional Information
Gene ID 24144
Other Names Tuftelin-interacting protein 11, Septin and tuftelin-interacting protein 1, STIP-1, TFIP11, STIP
Target/Specificity The synthetic peptide sequence is selected from aa 57-70 of HUMAN TFIP11
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFIP11
Synonyms STIP
Function Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
Cellular Location Cytoplasm. Nucleus. Note=In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles.
Research Areas
Citations (0)

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TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008 [PubMed 18367544]).


Saus, E., et al. J Psychiatr Res (2010) In press :
Tannukit, S., et al. Biochem. Biophys. Res. Commun. 390(3):1044-1050(2009)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
Stanek, D., et al. Mol. Biol. Cell 19(6):2534-2543(2008)
Patir, A., et al. Caries Res. 42(5):394-400(2008)

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$ 80.00
$ 99.00
Cat# BP20105a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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