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SELM Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q8WWX9
Other Accession NP_536355.1
Additional Information
Gene ID 140606
Other Names Selenoprotein M, SelM, SELM, SEPM
Target/Specificity The synthetic peptide sequence is selected from aa 132-145 of HUMAN SELM
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SELENOM {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:30397}
Function May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
Cellular Location Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Note=Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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Background

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. [provided by RefSeq].

References

Korotkov, K.V., et al. Mol. Cell. Biol. 22(5):1402-1411(2002)

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$ 277.78
Cat# BP20147b
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