SELM Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8WWX9 |
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Other Accession | NP_536355.1 |
Gene ID | 140606 |
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Other Names | Selenoprotein M, SelM, SELM, SEPM |
Target/Specificity | The synthetic peptide sequence is selected from aa 132-145 of HUMAN SELM |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SELENOM {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:30397} |
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Function | May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. |
Cellular Location | Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Note=Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. [provided by RefSeq].
References
Korotkov, K.V., et al. Mol. Cell. Biol. 22(5):1402-1411(2002)
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