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CD73 (NT5E) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P21589
Clone Names 2112707
Peptide ID 2112707
Additional Information
Gene ID 4907
Other Names 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, CD73, NT5E, NT5, NTE
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2014a was selected from the N-term region of human NT5E . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NT5E
Synonyms NT5, NTE
Function Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Research Areas
Citations (0)

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Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.


Hashikawa, T., et al., J. Dent. Res. 82(11):888-892 (2003).Rosi, F., et al., Biomed. Pharmacother. 56(2):100-104 (2002).Misumi, Y., et al., Eur. J. Biochem. 191(3):563-569 (1990).Boyle, J.M., et al., Hum. Genet. 81(1):88-92 (1988).Kalsi, K., et al., Mol. Cell. Biochem. 232 (1-2), 113-119 (2002).

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$ 80.00
Cat# BP2014a
Availability: In Stock
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