|Other Accession||Q5FVM1, NP_001070884.1|
|Other Names||Transmembrane protein 231, TMEM231|
|Target/Specificity||The synthetic peptide sequence is selected from aa 100-112 of HUMAN TMEM231|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).|
|Cellular Location||Cell projection, cilium membrane; Multi-pass membrane protein Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein is unknown.
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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