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ZNF516 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q92618 |
|---|---|
| Other Accession | NP_055458.1 |
| Gene ID | 9658 |
|---|---|
| Other Names | Zinc finger protein 516, ZNF516, KIAA0222 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 533-547 of HUMAN ZNF516 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZNF516 (HGNC:28990) |
|---|---|
| Function | Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress (PubMed:23446422). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q7TSH3}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF516 may be involved in transcriptional regulation.
References
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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