|Other Names||Dynein intermediate chain 2, axonemal, Axonemal dynein intermediate chain 2, DNAI2|
|Target/Specificity||The synthetic peptide sequence is selected from aa 499-513 of HUMAN DNAI2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Part of the dynein complex of respiratory cilia.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme|
|Tissue Location||Highly expressed in trachea and testis.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Loges, N.T., et al. Am. J. Hum. Genet. 83(5):547-558(2008)
Pennarun, G., et al. Hum. Genet. 107(6):642-649(2000)
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