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NSF Blocking Peptide (C-term)

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession P46459
Other Accession Q9QUL6, P46460, P18708, NP_006169.2
Additional Information
Gene ID 4905
Other Names Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF
Target/Specificity The synthetic peptide sequence is selected from aa 683-696 of HUMAN NSF
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NSF
Function Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

References

Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)
Hamza, T.H., et al. Nat. Genet. 42(9):781-785(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Parashuraman, S., et al. FEBS Lett. 584(6):1251-1256(2010)
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)

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$ 80.00
$ 99.00
Cat# BP20197B
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