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ANO4 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q32M45 |
|---|---|
| Other Accession | Q8C5H1, A6QLE6, NP_849148.2 |
| Gene ID | 121601 |
|---|---|
| Other Names | Anoctamin-4, Transmembrane protein 16D, ANO4, TMEM16D |
| Target/Specificity | The synthetic peptide sequence is selected from aa 203-216 of HUMAN ANO4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ANO4 |
|---|---|
| Synonyms | TMEM16D |
| Function | Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization. {ECO:0000250|UniProtKB:Q8C5H1} |
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a calcium-activated chloride channel.
References
Hartzell, H.C., et al. J. Physiol. (Lond.) 587 (PT 10), 2127-2139 (2009) :
Katoh, M., et al. Int. J. Oncol. 24(5):1345-1349(2004)
Katoh, M., et al. Int. J. Oncol. 22(6):1375-1381(2003)
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