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RNASE1 Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession P07998
Other Accession NP_937878.1
Additional Information
Gene ID 6035
Other Names Ribonuclease pancreatic, HP-RNase, RIB-1, RNase UpI-1, Ribonuclease 1, RNase 1, Ribonuclease A, RNase A, RNASE1, RIB1, RNS1
Target/Specificity The synthetic peptide sequence is selected from aa 29-42 of HUMAN RNASE1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RIB1, RNS1
Function Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
Cellular Location Secreted.
Tissue Location Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion)
Research Areas
Citations (0)

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This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq].


D'Alessio, G. Biopolymers 91(12):989-994(2009)
Kover, K.E., et al. J. Mol. Biol. 379(5):953-965(2008)
Ueki, M., et al. Biochem. Genet. 46 (3-4), 145-153 (2008) :
Johnson, R.J., et al. Biochemistry 46(36):10308-10316(2007)
Cybulski, C., et al. Urol. Int. 79(1):44-49(2007)

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$ 80.00
$ 99.00
Cat# BP20222a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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