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GUCA1C Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession O95843
Other Accession NP_005450.3
Additional Information
Gene ID 9626
Other Names Guanylyl cyclase-activating protein 3, GCAP 3, Guanylate cyclase activator 1C, GUCA1C, GCAP3
Target/Specificity The synthetic peptide sequence is selected from aa 186-199 of HUMAN GUCA1C
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCA1C
Synonyms GCAP3
Function Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)- sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Tissue Location Retina.
Research Areas
Citations (0)

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Background

GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

References

Stephen, R., et al. J. Mol. Biol. 359(2):266-275(2006)
Imanishi, Y., et al. Eur. J. Neurosci. 15(1):63-78(2002)
Haeseleer, F., et al. J. Biol. Chem. 274(10):6526-6535(1999)

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$ 80.00
$ 99.00
Cat# BP20239B
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