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ATP5S Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession Q99766
Other Accession Q4R5S4, NP_001003803.1
Additional Information
Gene ID 27109
Other Names ATP synthase subunit s, mitochondrial, ATP synthase-coupling factor B, FB, Mitochondrial ATP synthase regulatory component factor B, ATP5S, ATPW
Target/Specificity The synthetic peptide sequence is selected from aa 51-64 of HUMAN ATP5S
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP5S
Synonyms ATPW
Function Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway (By similarity).
Cellular Location Mitochondrion. Mitochondrion inner membrane
Research Areas
Citations (0)

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Background

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.

References

Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Cross, R.L. Nature 427(6973):407-408(2004)
Oster, G., et al. Trends Cell Biol. 13(3):114-121(2003)
Leyva, J.A., et al. Mol. Membr. Biol. 20(1):27-33(2003)
Belogrudov, G.I., et al. J. Biol. Chem. 277(8):6097-6103(2002)

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$ 80.00
$ 99.00
Cat# BP20241A
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