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PTRH2 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y3E5 |
|---|---|
| Other Accession | NP_057161.1 |
| Gene ID | 51651 |
|---|---|
| Other Names | Peptidyl-tRNA hydrolase 2, mitochondrial, PTH 2, Bcl-2 inhibitor of transcription 1, PTRH2, BIT1, PTH2 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 41-55 of HUMAN PTRH2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PTRH2 |
|---|---|
| Synonyms | BIT1, PTH2 |
| Function | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. |
| Cellular Location | Mitochondrion outer membrane; Single-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
References
Fan, T., et al. Int. J. Oncol. 35(2):359-367(2009)
Biliran, H., et al. J. Biol. Chem. 283(42):28029-28037(2008)
Bouchentouf, M., et al. Am. J. Transplant. 7(6):1491-1505(2007)
Jan, Y., et al. Cell 116(5):751-762(2004)
De Pereda, J.M., et al. J. Biol. Chem. 279(9):8111-8115(2004)
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