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RAB27A Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession P51159
Other Accession Q99P74, Q99P58, P23640, Q4LE85, Q9ERI2, NP_004571.2
Additional Information
Gene ID 5873
Other Names Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
Target/Specificity The synthetic peptide sequence is selected from aa 151-164 of HUMAN RAB27A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB27A
Synonyms RAB27
Function Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Cellular Location Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles
Tissue Location Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.


Ohbayashi, N., et al. Pigment Cell Melanoma Res 23(3):365-374(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Meeths, M., et al. Pediatr Blood Cancer 54(4):563-572(2010)
Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
Wood, S.M., et al. Blood 114(19):4117-4127(2009)

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$ 80.00
$ 99.00
Cat# BP20264b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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