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CPSF6 Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession Q16630
Other Accession Q6DDW4, Q6NVF9, Q6NWC6, Q5ZL34, Q0P5D2, NP_008938.2
Additional Information
Gene ID 11052
Other Names Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68 kDa subunit, CFIm68, CPSF 68 kDa subunit, Pre-mRNA cleavage factor Im 68 kDa subunit, Protein HPBRII-4/7, CPSF6, CFIM68
Target/Specificity The synthetic peptide sequence is selected from aa 38-51 of HUMAN CPSF6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPSF6
Synonyms CFIM68
Function Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Cellular Location Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles
Research Areas
Citations (0)

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The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.


Lee, K., et al. Cell Host Microbe 7(3):221-233(2010)
Ruepp, M.D., et al. Mol. Biol. Cell 20(24):5211-5223(2009)
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28(23):7050-7065(2008)
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)

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$ 80.00
$ 99.00
Cat# BP20278a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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