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PROX-1-S514 Antibody Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92786
Peptide ID 26537
Additional Information
Gene ID 5629
Other Names Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1, PROX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PROX1
Function Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Cellular Location Nucleus {ECO:0000250|UniProtKB:P48437}. Note=RORG promotes its nuclear localization {ECO:0000250|UniProtKB:P48437}
Tissue Location Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)Zhang, C., et al. Clin. Chim. Acta 411 (5-6), 395-399 (2010) Suresh, S., et al. FEBS J. 277(4):951-963(2010)

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$ 80.00
Cat# BP2035e
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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