ESCO1 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5FWF5 |
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Other Accession | Q69Z69 |
Gene ID | 114799 |
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Other Names | N-acetyltransferase ESCO1, 231-, CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1, ESCO1, EFO1, KIAA1911 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ESCO1 |
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Synonyms | EFO1, KIAA1911 |
Function | Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15958495, PubMed:18614053). Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3 (PubMed:18614053). |
Cellular Location | Nucleus. Chromosome Note=Nuclear at interphase, associated with chromosomes during mitosis |
Tissue Location | Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
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