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ESCO1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q5FWF5
Other Accession Q69Z69
Additional Information
Gene ID 114799
Other Names N-acetyltransferase ESCO1, 231-, CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1, ESCO1, EFO1, KIAA1911
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESCO1
Synonyms EFO1, KIAA1911
Function Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Cellular Location Nucleus. Chromosome. Note=Nuclear at interphase, associated with chromosomes during mitosis (PubMed:15958495)
Tissue Location Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle.
Research Areas
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Background

Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.

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$ 80.00
Cat# BP20370b
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