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TCF7L1 Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession Q9HCS4
Additional Information
Gene ID 83439
Other Names Transcription factor 7-like 1, HMG box transcription factor 3, TCF-3, TCF7L1, TCF3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCF7L1
Synonyms TCF3
Function Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.
Cellular Location Nucleus.
Tissue Location Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium
Research Areas
Citations (0)

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Background

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

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$ 80.00
Cat# BP20423a
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