PITPNA Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q00169 |
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Other Accession | P16446, P48738, P53810, Q2HJ54 |
Gene ID | 5306 |
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Other Names | Phosphatidylinositol transfer protein alpha isoform, PI-TP-alpha, PtdIns transfer protein alpha, PtdInsTP alpha, PITPNA, PITPN |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PITPNA |
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Synonyms | PITPN |
Function | Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:22822086, PubMed:15522822, PubMed:18636990, PubMed:14962392). Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (PubMed:15522822, PubMed:22822086). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (PubMed:22822086). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P53810}. Nucleus {ECO:0000250|UniProtKB:P53810} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
References
Dickeson S.K., et al. Gene 142:301-305(1994).
Tanaka S., et al. Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
Lubec G., et al. Submitted (MAR-2007) to UniProtKB.
Rikova K., et al. Cell 131:1190-1203(2007).
Choudhary C., et al. Science 325:834-840(2009).
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