|Other Names||Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, B3Gal-T8, Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1, 3-galactosyltransferase 1, Beta-1, 3-galactosyltransferase, Core 1 beta1, 3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1, C1GALT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Widely expressed. Highly expressed in kidney, heart, placenta and liver.|
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Provided below are standard protocols that you may find useful for product applications.
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Ju T., et al. J. Biol. Chem. 277:178-186(2002).
Jensen M.P.A., et al. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., et al. Nature 424:157-164(2003).
Scherer S.W., et al. Science 300:767-772(2003).
Ju T., et al. Proc. Natl. Acad. Sci. U.S.A. 99:16613-16618(2002).
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