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R Cebpd Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q03484
Additional Information
Gene ID 25695
Other Names CCAAT/enhancer-binding protein delta, C/EBP delta, Transcription factor CELF, Cebpd, Celf
Target/Specificity The synthetic peptide sequence is selected from aa 176-189 of Rat Cebpd
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cebpd
Synonyms Celf
Function Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:1714459). Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (By similarity).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages (By similarity).

References

Kageyama R., et al. J. Biol. Chem. 266:15525-15531(1991).

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$ 80.00
Cat# BP20492c
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