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SLC25A25 Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession Q6KCM7
Other Accession Q7ZYD5, Q8K3P6, A2ASZ8, Q0V7M4, A2CEQ0
Additional Information
Gene ID 114789
Other Names Calcium-binding mitochondrial carrier protein SCaMC-2, Mitochondrial ATP-Mg/Pi carrier protein 3, Mitochondrial Ca(2+)-dependent solute carrier protein 3, Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25, SLC25A25, APC3, KIAA1896, MCSC3, SCAMC2
Target/Specificity The synthetic peptide sequence is selected from aa 82-93 of Human SLC25A25
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A25 (HGNC:20663)
Function Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus [Isoform 2]: Expression is restricted to kidney and lung.
Research Areas
Citations (0)
citation

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Background

Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.

References

del Arco A., et al. J. Biol. Chem. 279:24701-24713(2004).
Fiermonte G., et al. J. Biol. Chem. 279:30722-30730(2004).
Nagase T., et al. DNA Res. 8:179-187(2001).
Clark H.F., et al. Genome Res. 13:2265-2270(2003).
Ota T., et al. Nat. Genet. 36:40-45(2004).

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$ 277.78
Cat# BP20508a
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