SLC25A25 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6KCM7 |
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Other Accession | Q7ZYD5, Q8K3P6, A2ASZ8, Q0V7M4, A2CEQ0 |
Gene ID | 114789 |
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Other Names | Calcium-binding mitochondrial carrier protein SCaMC-2, Mitochondrial ATP-Mg/Pi carrier protein 3, Mitochondrial Ca(2+)-dependent solute carrier protein 3, Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25, SLC25A25, APC3, KIAA1896, MCSC3, SCAMC2 |
Target/Specificity | The synthetic peptide sequence is selected from aa 82-93 of Human SLC25A25 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC25A25 (HGNC:20663) |
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Function | Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus [Isoform 2]: Expression is restricted to kidney and lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
References
del Arco A., et al. J. Biol. Chem. 279:24701-24713(2004).
Fiermonte G., et al. J. Biol. Chem. 279:30722-30730(2004).
Nagase T., et al. DNA Res. 8:179-187(2001).
Clark H.F., et al. Genome Res. 13:2265-2270(2003).
Ota T., et al. Nat. Genet. 36:40-45(2004).
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