|Other Names||Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, CD90, THY1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2050a was selected from the N-term region of human THY1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
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CD90 (Thy1) antigen is a GPI linked glycoprotein member of the Immunoglobulin superfamily. It is expressed on murine T cells, thymocytes, neural cells, cells of granulocytic lineage, early hematopoietic progenitors, fibroblasts, neurons and Kupffer's cells. Thy1 may play a role in cell to cell or cell to ligand interactions during synaptogenesis and other events in the brain.
Koumas, L., et al., Am. J. Pathol. 163(4):1291-1300 (2003).Abeysinghe, H.R., et al., Cancer Genet. Cytogenet. 143(2):125-132 (2003).Saalbach, A., et al., Microvasc. Res. 64(1):86-93 (2002).Henniker, A.J., J. Biol. Regul. Homeost. Agents 15(4):392-393 (2001).Ye, Z., et al., Biochem. Biophys. Res. Commun. 275(1):223-227 (2000).
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