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M Tfap2c Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession Q61312
Additional Information
Gene ID 21420
Other Names Transcription factor AP-2 gamma, AP2-gamma, AP-22, Activating enhancer-binding protein 2 gamma, Tfap2c, Tcfap2c
Target/Specificity The synthetic peptide sequence is selected from aa 133-144 of Mouse Tfap2c
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tfap2c
Synonyms Tcfap2c
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Cellular Location Nucleus.
Tissue Location Expressed in lung, ovary and testis. Expressed in most squamous epithelia. Also, detected in several exocrine glands including the prostate, the preputial and salivary glands, serous glands of the tongue and ocular harderian glands
Research Areas
Citations (0)

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Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

References

Oulad-Abdelghani M., et al. Exp. Cell Res. 225:338-347(1996).
Carninci P., et al. Science 309:1559-1563(2005).
Church D.M., et al. PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Yahata T., et al. Genomics 80:601-613(2002).

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$ 80.00
Cat# BP20531a
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